Glutathione Depletion, Lipid Peroxidation, and Liver Necrosis following Bromobenzene and lodobenzene Intoxication
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چکیده
منابع مشابه
Ameliorating effects of genestein: Study on mice liver glutathione and lipid peroxidation after irradiation
Background: Genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. Radiation–induced free radicals in turn impair the antioxidative defense mechanism, leading to an increased membrane lipid peroxidation that results in damage of the membrane bound enzyme and may lead to damage or death of cell. Hence, the lipid peroxidation is a good biomar...
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STUDY OBJECTIVE Neutrophils are involved in acute lung injury during ARDS via several mechanisms. This study focuses on neutrophil-derived oxidative stress. Hypochlorite is a major neutrophil-derived oxidant. This study characterizes hypochlorite-induced acute changes in pulmonary circulation and the involvement of tissue lipid peroxidation (LPO) and reduced glutathione (rGSH) depletion. METH...
متن کاملCyclophosphamide-Induced Lipid Peroxidation and Changes in Cholesterol Content: Protective Role of Reduced Glutathione
The study was designed with an aim to evaluate the protective effects of reduced glutathione on cyclophosphamide induced lipid peroxidation and also changes in cholesterol content. Goat liver and white New Zealand rabbit were used as lipid source for the models. Lipid peroxidation study was performed by measuring the malondial...
متن کاملGlutathione protects liver and kidney tissue from cadmium- and lead-provoked lipid peroxidation
Cd and Pb represent a serious ecological problem due to their soluble nature, their mobility and ability to accumulate in the soil. The exposure to these heavy metals can originate from different sources (drinking water, food and air), and they can enter into the human body through the respiratory and digestive systems. The effects of glutathione on Cd and Pb accumulation and lipid peroxidation...
متن کاملameliorating effects of genestein: study on mice liver glutathione and lipid peroxidation after irradiation
background: genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. radiation–induced free radicals in turn impair the antioxidative defense mechanism, leading to an increased membrane lipid peroxidation that results in damage of the membrane bound enzyme and may lead to damage or death of cell. hence, the lipid peroxidation is a good biomarker of da...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 1984
ISSN: 0192-6233,1533-1601
DOI: 10.1177/019262338401200315